Assoc. Prof. Dr. Ayşe Burcu Akıncı

Pediatric hematology and oncology services are provided at VM Medicalpark Pendik.

Hematopoietic stem cell transplantation

Leukemias

Lymphoma

Neuroblastoma

Thalassemia

Blood transfusion

Bone marrow failure syndromes

Benign hematology

1998–2005: Marmara University, English Medical Program — Undergraduate/Graduate Medical Education

2005–2010: Okmeydanı Training and Research Hospital, Department of Pediatrics — Residency

2013–2016: Ege University Faculty of Medicine, Division of Pediatric Hematology and Oncology — Fellowship

2018 — Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi — Assistant Professor

2018–2024 — Acıbadem Mehmet Ali Aydınlar Üniversitesi Tıp Fakültesi — Assistant Professor

2018–2024 — Acıbadem Altunizade Hastanesi — Pediatric Bone Marrow Transplantation

25.09.2015 — Turkish Society of Hematology

05.06.2015 — Turkish Society of Pediatric Hematology

02.02.2018 — Turkish Society of Pediatric Oncology

06.09.2018 — Turkish Medical Association

01.04.2021 — Controversial Topics and Difficult Cases — Türk Hematoloji Derneği; online

06.02.2021 — Central Nervous System Tumours I — Türk Pediatrik Hematoloji Derneği; online

28.11.2020 — TPOG Long-Term Follow-Up Guidelines, UDİR I — Türk Pediatrik Hematoloji Derneği; webinar

22–23.03.2019 — Basic Faculty Development for Medical Educators — Acıbadem Üniversitesi; İstanbul

09.2017–03.2018 — Transfusion Medicine, Blood Banking and Hemapheresis Masterclass — Türk Hematoloji Derneği Kanbilim Akademisi; İzmir

25.03.2017 — Pediatric Solid Tumours — Türk Pediatrik Onkoloji Derneği; İzmir

19–20.11.2016 — Leukemia School — Türk Pediatrik Hematoloji Derneği; Ankara

24.09.2016 — Bone and Soft-Tissue Sarcomas — Türk Pediatrik Onkoloji Derneği; Ankara

19.03.2016 — Central Nervous System Tumours — Türk Pediatrik Onkoloji Derneği; İstanbul

19–20.12.2015 — Practical Hemostasis and Thrombosis Laboratory — Türk Hematoloji Derneği; Antalya

12–13.09.2015 — Hematopoietic Stem Cell Transplantation — Türk Hematoloji Derneği; Ankara

06–14.06.2015 — Medical Statistics in Clinical Research — Ege Üniversitesi; İzmir

14–15.02.2015 — Basic Immunology and Flow Cytometry — Türk Hematoloji Derneği; Antalya

15–16.11.2014 — Bone Marrow Failure in Pediatric Hematology and Oncology — Türk Pediatrik Hematoloji Derneği; Ankara

13–17.05.2014 — Radiotherapy for Pediatric Oncologists — XIII. Ulusal Pediatrik Kanser Kongresi; Bodrum

13–17.05.2014 — Nutrition — XIII. Ulusal Pediatrik Kanser Kongresi; Bodrum

15–16.02.2014 — Transfusion School for Pediatric Hematology Fellows — Türk Pediatrik Hematoloji Derneği; Ankara

21–22.12.2013 — Basic Good Clinical Practice — Türk Hematoloji Derneği; Antalya

01.03.2008 — Thyroid and Obesity — İstanbul Üniversitesi İstanbul Tıp Fakültesi; İstanbul

09.02.2008 — Short Stature, Precocious and Delayed Puberty — İstanbul Üniversitesi İstanbul Tıp Fakültesi; İstanbul

1. Akıncı B, Atay D, Demir Yenigürbüz F, Akçay A, Akar O, Öztürk G. Fatal disseminated Magnusiomyces clavatus infection with rash in pediatric acute lymphoblastic leukemia: A case report. Diagnostic Microbiology & Infectious Disease 2024;108:116148. Doi:0.1016/j.diagmicrobio.2023.116148.

2. Akıncı B, Demir Yenigürbüz F, Üstyol A, Ökdemir D. Thyroid Dysfunction in Beta-Thalassemia Major: Is It Related to Autoimmunity or Iron Overload? Acıbadem Univ. Sağlık Bilim. Derg. 2023; 14 (3): 377-382. Doi:10.31067/acusaglik.1097646.

3 Güzelküçük Z, Yılmaz Karapınar D, Aylan Gelen S, Tokgöz H, Özcan A, Ay Y, Bahadır A, Özbek NY, Ören A Canbolat Ayhan A, Akyay A, Akıncı B, Karadaş N, Ünüvar A, Ören H, Fettah A, Kaya Z, Işık B, Eker İ, Karaman S, Türedi Yıldırım A, Orhan MF, Oymak Y, Timur C, Yazıcı N, Şimşek A, Karakurt N, Töret E, Sezgin Evim M. Central Nervous System thrombosis in pediatric acute lymphoblastic leukemia in Turkey: A multicenter study. Pediatric Blood and Cancer. 2023;e30425. Doi:10.1002/pbc.30425.

4. Cokyaman T, Sınmaz Y, Aylanc N, Akıncı AB, Sözeri B. Diagnostic inexperience of Takayasu arteritis in pediatric neurology: a case report and mini-review of the literature. Osmangazi Journal of Medicine. 2023;45(1):135-141. Doi:10.20515/otd.1176704.

5. Demir Yenigürbüz D, Atay D, Akıncı B, Akçay A, Öztürk G. Respiratory viral infections in the pediatric hematopoietic stem cell transplant population: progression to lower respiratory tract disease. J Pediatr Hematol Oncol. 2023;45(1):e75. Doi: 10.1097/MPH0000000000002525.

6. Akçay A, Atay D, Erbey F, Akıncı B, Yenigürbüz FD, Eyüboğlu F, Ovalı E, Öztürk G. Safety and efficacy of co-transplantation of hematopoietic stem cells combined with human umbilical cord-derived mesenchymal stem cells in children with severe aplastic anemia: a single-center experience. Exp Clin Transplant. 2022;12:1114-1121. Doi: 10.6002/ect.2021.0027.

7. Akıncı B, Atay D, Demir Yenigürbüz F, Akçay A, Öztürk G. Therapeutic plasma exchange in pediatric patients with sinusoidal obstruction syndrome/veno-occlusive disease after hematopoietic stem cell transplantation: a single center experience. Exp Clin Transplant. 2022;20(7):680-688. Doi: 10.6002/ect.2021.0475.

8. Yeşilipek MA, Uygun V, Küpesiz A, Karasu G, Öztürk G, Ertem M, Şaşmaz İ, Daloğlu H, Güler E, Hazar V, Fışgın T, Sezgin G, Kansoy S, Kuşkonmaz B, Akıncı B, Özbek N, Ünal İnce E, Öztürkmen S, Tayfun Küpesiz F, Yalçın K, Anak S, Bozkurt C, Karakükçü M, Küpeli S, Albayrak D, Öniz H, Aksoylar S, Okur FV, Albayrak C, Demir Yenigürbüz F, Ok Bozkaya İ, İleri T, Gürsel O, Karagün BŞ, Tüysüz Kintrup G, Çelen S, Elli M, Adaklı Aksoy B, Yılmaz E, Tanyeli A, Turan Akyol Ş, Önder Siviş Z, Özek G, Uçkan D, Kartal İ, Atay D, Akyay A, Arman Bilir Ö, Çakmaklı HF, Kürekçi E, Malbora B, Akbayram S, Demir HA, Çakı Kılıç S, Güneş AM, Zengin E, Özmen S, Antmen AB. Thalassemia-free and graft-versus-host-free survival: outcomes of hematopoietic stem cell transplantation for thalassemia major, Turkish experience. Bone Marrow Transplantation. 2022;57:760-767. Doi: 10.1038/s41409-022-01613-w.

9. Akıncı B, Akçay A, Demir Yenigürbüz F, Atay D, Öztürk G. The impact of panel reactive antibodies and different desensitization methods on pediatric allogeneic hematopoietic stem cell transplantation outcomes. J Pediatr Hematol Oncol. 2022;44(3):689-694. Doi: 10.1097/MPH.0000000000002357.

10. Akinci B, Yenigurbuz FD, Tuncez E, Oz Ozlem. Beta-thalassemia mutation types and the relationship with the demographic factors in Sanliurfa, Turkey. Family Practice and Palliative Care. 2021;6(3):105-110. Doi.org/10.22391/fppc.805164.

11. Atay D, Akçay A, Akıncı B, Yenigürbüz FD, Ovali E, Öztürk G. Co-transplantation of mesenchymal stromal cell and haploidentical hematopoietic stem cell with TCR αβ depletion in children with primary immunodeficiency syndromes. Pediatric Transplantation. 2021;25:e14120. Doi.org/10.111/petr.14120.

12. Atay D, Akçay A, Yenigürbüz FD, Akıncı B, Bagirova K, Hasanova S, Öztürk G. Clinical study of graft-versus-host disease prophylaxis in unrelated hematopoietic stem cell transplantation for pediatric nonmalignant diseases with different doses anti-human T-lymphocyte immunoglobulin. Pediatric Transplantation. 2021;25:e14098. Doi.org/10.1111/petr.14098.

13. Tayfun Kupesiz F, Ocak S, Sirin Koc B, Sezgin Evim M, Tufekci O, Tuysuz Kintrup G, Aygünes U, Eker İ, Unver Koluman B, İlhan G, Andic N, Toret E, Akinci AB, Tatli Gunes B, Yilmaz F, Gurlek Gokcebay D, Belgemen Ozer T, Isik M, Oymak Y, Atesagaoglu B, Erdogan Ozunal I, Duran M, Ozel Erkan D, Gurpinar E, Aydinok Y. Evaluation of the knowledge of intern doctors on transfusion medicine in Turkey. Transfuze Hematol Dnes. 2020:26(3):201-211. Doi:10.21203/rs.2.22224/v1.

14. Karapınar DY, Şahin A, Özen S, Yazıcı Özkaya, P, Önder Siviş Z, Akıncı AB, Özdemir Karadas N, Karapınar B. Hyponatremia in children with acute lymphoblastic leukemia. J Pediatr Res. 2020;7(2):139-45. Doi: 10.4274/jpr.galenos.2019.46547.

15. Yilmaz Karapinar D, Özdemir HH, Akinci B, Yaşar AŞ, Siviş ZÖ, Onay H, Özkinay F. Management of a patient with congenital biallelic CSF3R mutation with GM-CSF. J Pediatr Hematol Oncol. 2020;42(3):e164-e166. Doi:10.1097/MPH.00000000001359.

16. Akıncı B, Hekimci Özdemir H, Özdemir Karadas N, Şahin Yaşar A, Önder Siviş Z, Aydınok Y, Kavaklı K, Balkan C, Yılmaz Karapınar D. Retrospective Evaluation of Childhood Cutaneous Mastocytosis Cases. J Pediatr Res. 2020;7(1):13-7. Doi: 10.4274/jpr.galenos.2019.98105.

17. Karapınar DY, Patıroğlu T, Metin A, Çalışkan Ü, Celkan T, Yılmaz B, Karakaş Z, Karapınar TH, Akıncı B, Özkınay F, Onay F, Yeşilipek MA, Akar HH, Tüysüz G, Tokgöz H, Özdemir GH, Aslan Kıykım A, Karaman S, Kılınç Y, Oymak Y, Küpesiz A, Olcay L, Keskin Yıldırım Z, Aydoğan G, Gökçe M, İleri T, Aral YZ, Bay A, Atabay B, Kaya Z, Söker M, Özdemir Karadaş N, Özbek N, Özsait Selçuk B, Özdemir HH, Uygun V, Tezcan Karasu G, Yılmaz Ş. Homozygous c.130-131 ins A (pW44X) mutation in the HAX1 gene as the most common cause of congenital neutropenia in Turkey: Report from the Turkish Severe Congenital Neutropenia Registry. Pediatr Blood Cancer. 2019;66(10):e27923. Doi: 10.1002/pbc.27923.

18. Akıncı B, Yasar AS, Özdemir Karadas N, Önder Sivis Z, Hekimci Özdemir H, Yılmaz Karapinar D, Balkan C, Kavakli K, Aydinok Y. Fertility in patients with thalassemia and outcome of pregnancies: a Turkish experience. Turk J Haematol. 2019;36(4):274-277. Doi:10.4274/tjh.galenos.2019.2019.0025.

19. Yazal Erdem A, Demir Yenigürbüz FD, Pekpak E, Akıncı B, Aktekin E, Bayram C, Yıldırmak ZY, Ataseven E, Akbayram S, Şaşmaz İ, Taburoğlu Yılmaz B, Özkan A, Akpınar Tekgündüz S, Köse D, Karapınar T, Büyükavcı M, Sal E, Bayhan T, Kirkiz S, Ünal Ş, Vergin RC, Çil M, Malbora B, Ayçiçek A, Yaralı HN, Özbek NY. Refugee children with beta-thalassemia in Turkey: Overview of demographic, socioeconomic, and medical characteristics. Pediatr Blood Cancer. 2019;66:e27636. Doi:10.1002/pbc.27636.

20. Yılmaz Karapınar D, Akıncı B, Şahin Yaşar A, Hekimci Özdemir H, Önder Siviş Z, Onay H, Özkınay F. Congenital neutropenia patient with biallelic CSF3R mutation responding to CCSF. J Pediatr Hematol Oncol. 2019;41:e190-e192. Doi: 10.1097/MPH.0000000000001258.

21.Akıncı B, Çetingül N, Özdemir Ö, Kamer S, Kantar M, Aksoylar S, Demirağ B, Vergin C, Öniz H, Kansoy S, Turhan T, Akalın T, Ertan Y, Kitiş Ö, Anacak Y. Is there an increased risk of spinal relapse in standard-risk medulloblastoma/primitive neuroectodermal tumor patients who receive only a reduced dose of craniospinal radiotherapy? Childs Nerv Syst. 2018;34(9):1657-1662. Doi: 10.1007/s00381-018-3842-6.

22. Akıncı B, Siviş ZÖ, Şahin A, Karapınar DY, Balkan C, Kavaklı K, Aydınok Y. Stevens-Johnson syndrome associated with methotrexate treatment for acute lymphoblastic leukemia:a case report. Arch Argent Pediatr. 2018;116(3):e459-e462. Doi: 10.5546/aap.2018.eng.e459.

23.Akıncı B, Duyu M, Alkılıç L, Karapinar DY, Karapinar B. Inferior petrosal sinus thrombosis in a child due to malposition of central venous catheter: a case report. Med Princ Pract. 2017;26(6):579-581. Doi: 10.1159/000484637.

24. Avcu G, Karapinar DY, Akıncı AB, Siviş ZO, Şahin A, Bal ZS, Polat SH, Metin DY, Vardar F, Aydinok Y. Utility of serum galactomannan assay for the diagnosis of invasive aspergillosis in children with acute lymphoblastic leukemia. Int J Infect Dis. 2017;54:8-12. Doi: 10.1016/j.ijid.2016.10.027.

25. Zeytinoğlu A, Turhan A, Keskinoğlu A, Aksoylar S, Dincel N, Deveci B, Tutkun E. The first two ganciclovir resistant cytomegalovirus isolates from kidney and pediatric stem cell transplant recipients in Turkey. J Immunol Clin Microbiol. 2016;1 (3). Doi.org/10.5455/jicm.12.2016070.

26. Şahbudak ZB, Karapınar DY, Karadaş N, Sen S, Sivis ZO, Akıncı AB, Balkan C, Kavakli K, Vardar F, Aydınok Y. Proven and probable invasive fungal infections in children with acute lymphoblastic leukaemia: results from an university hospital, 2005-2013. Mycoses. 2015;58:225-232. Doi: 10.1111/myc.12303.

27. Kafadar İ, Akıncı AB, Pekün F, Adal E. The role of serum zinc level in febrile convulsion etiology. J Pediatr Inf. 2012;6:90-93. Doi:10.5152/ced.2012.27.

1. Demir Yenigürbüz F, Akıncı B, Üstyol A, Ökdemir D, Sezer A. Endocrine complications in pediatric beta-thalassemia majör patients: a single center experience. Journal of Harran University Medical Faculty. 2022;19(3):556-562. Doi:10.35440/hutfd.1144199.

2. Küpesiz TF, Andıç N, Evim MS, Eker İ, Yılmaz AF, Kintrup GT, Gökçebay DG, Oymak Y, Ateşağaoğlu B,Özer TB, Özünal IE, Işık M, Aygün U, İlhan G, Töret E, Akıncı AB, Tüfekçi Ö, Güneş BT, Koç BŞ, Koluman BÜ, Ocak S, Duran M, Erkan DÖ, Gürpınar E, Aydinok Y. Evaluation of the achievement of hematologists to transfusion medicine education with self-assessment questionnaire in Turkey. Tıp Eğitimi Dünyası. 2020;19(58):128-143. Doi.org/10.25282/ted.658903.

1. Lanzkowsky’nin Pediatrik Hematoloji ve Onkoloji El Kitabı, Bölüm Adı: Hematopoietik Kök Hücre Nakli ve Hücresel Tedaviler (2024)., Akıncı Ayşe Burcu. Editör: Ali Bülent Antmen, Barbaros Şahin Karagün, ISBN: 978-625-99024-4-9. Sayfa 576-594, Türkçe (Kitap Çevirisi)

2. Çocuk Hematolojide Olgularla Akut Lösemiler, Bölüm adı:(Akut Lenfoblastik Lösemili Bir Olguda Gelişen Hipertrigliserideminin Plazmaferez ile Başarılı Tedavisi) (2021)., Akıncı Ayşe Burcu, Galenos Yayınevi, Editör: Özbek NM, Güneş AM, Ören H, Yaralı HN, ISBN:978-605-06264-9-0, Sayfa 221-222, Türkçe (Bilimsel Kitap)

3. Çocuk Hematolojide Olgularla Akut Lösemiler, Bölüm adı:(Tip B Laktik Asidoz ve Bilateral Renal Tutulum ile Başvuran Akut Lenfoblastik Lösemi Olgusu) (2021)., Akıncı Ayşe Burcu, Galenos Yayınevi, Editör: Özbek NM, Güneş AM, Ören H, Yaralı HN, ISBN:978-605-06264-9-0, Sayfa:44-46, Türkçe (Bilimsel Kitap)

4. Talaseminin Klinik Yönetim Rehberi, Bölüm adı:(Kan Transfüzyon) (2016)., Akıncı Ayşe Burcu, Uluslararası Talasemi Federasyonu Yayını, Editör:Aydınok Y, Tanyeli A, Ünal S, Kılınç Y, Malyalı D, ISBN:978-9963-717-06-04, Sayfa 30-43, Türkçe (Kitap Çevirisi)