Prof. Dr. İbrahim Toprak

1998–2004: Dokuz Eylül University Faculty of Medicine.

2004–2010: Ophthalmology residency, Pamukkale University Faculty of Medicine.

2019: Cornea, Cataract and Refractive Surgery fellowship with Prof. Jorge L. Alió, Vissum Instituto Oftalmológico, Alicante, Spain.

2023: Corneal surgery with Prof. Massimo Busin, Ospedale Privati Forli, Italy.

2024: Refractive surgery with Prof. Suphi Taneri, St. Franziskus Hospital Münster, Germany.

2017–2019: Assistant Professor, Pamukkale University Faculty of Medicine.

2019–2025: Associate Professor, Pamukkale University Faculty of Medicine.

2025–2026: Professor, Pamukkale University Faculty of Medicine.

2026: Head of Ophthalmology, Pamukkale University Faculty of Medicine.

2026: Ophthalmology specialist / Professor, Liv Hospital Ulus.

2017–2026: Ophthalmology faculty member, Pamukkale University Faculty of Medicine Hospital.

2010–2017: Ophthalmology specialist, Denizli Servergazi State Hospital.

Early diagnosis and treatment of keratoconus and corneal ectasia; pediatric and adolescent keratoconus.

Corneal cross-linking (CXL), personalized protocols for ultra-thin corneas, and combined laser/CXL Cretan and Athens protocols.

Femtosecond laser-assisted intracorneal ring segments (ICRS).

Assessment and treatment of post-laser ectasia and vision problems.

Corneal transplantation (keratoplasty).

Pre-laser suitability assessment and detection of at-risk eyes; No-Touch PRK, PRK and Femto-LASIK (i-LASIK) for myopia, astigmatism and hyperopia.

Phakic intraocular lenses for high prescriptions and eyes unsuitable for laser.

Cataract surgery (phacoemulsification); personalized assessment and selection of multifocal, EDOF and toric lenses.

Glaucoma diagnosis, follow-up, medication and laser treatment; trabeculectomy and Ahmed glaucoma valve implantation.

Corneal ulcers and infections, dry eye and allergies, stem cell deficiency, ocular surface infections and tumors, and pterygium surgery.

Cornea and Ocular Surface Unit, Turkish Ophthalmological Association.

Cataract and Refractive Surgery Unit, Turkish Ophthalmological Association.

European Vision and Eye Research (EVER).

Royal College of Surgeons of Edinburgh (MRCSEd).

2020–2026: Editorial board member, BMC Ophthalmology.

Akyol T, Parca O, Un ES, Toprak I, Pekel G (2026). Beyond the Cornea: Early Changes in Scleral, Iris, and Corneal Parameters After Corneal Collagen Cross-Linking. Journal of Clinical Medicine, 15(12): 4428.

Toprak I, Gunes CE, Martin-Seker C, Parca O (2025). A novel metric to monitor early progression in keratoconus: epithelial backscatter. International Ophthalmology, 45(1): 253.

Kanclerz P, Przewlocka K, Toprak I, Alio J (2023). The prevalence of keratoconus in northern Poland: A cross-sectional study of patients from a primary healthcare practice. Contact Lens & Anterior Eye, 46(4): 101846.

Toprak I, Cavas F, Velázquez JS, Alio Del Barrio JL, Alio JL (2023). A three-dimensional morpho-volumetric similarity study of Down syndrome keratopathy vs. keratoconus. Eye and Vision, 10(1): 4.

Toprak I (2023). To what extent is pregnancy-induced keratoconus progression reversible? A case report and literature review. European Journal of Ophthalmology, 33(1): NP37-NP41.

Toprak I, Kilic D (2022). Current clinical approach to pediatric keratoconus patients. Expert Review of Ophthalmology, 17(2): 105-114.

Toprak I, Cetin EN, Akbulut S, Pekel G, Yuksel S, Cobankara V (2022). Enhanced ectasia screening in patients with uveitis and isolated systemic inflammatory disease. Ocular Immunology and Inflammation, 30(2): 324-329.

Toprak I, Gunes CE (2021). Increased epithelial backscatter: A novel finding in subclinical and clinical keratoconus. Clinical & Experimental Ophthalmology, 49(9): 1000-1008.

Toprak I, Cavas F, Velázquez JS, Alio Del Barrio JL, Alio JL (2021). Three-dimensional morphogeometric and volumetric characterization of cornea in pediatric patients with early keratoconus. American Journal of Ophthalmology, 222: 102-111.

Toprak I, Cavas F, Vega A, Velázquez JS, Alio Del Barrio JL, Alio JL (2021). Evidence of a Down Syndrome Keratopathy: A Three-dimensional (3-D) Morphogeometric and Volumetric Analysis. Journal of Personalized Medicine, 11(2): 82.

Toprak I, Vega A, Espla E, Alio Del Barrio JL, Cavas F, Alio JL (2021). Diagnostic value of corneal epithelial and stromal thickness distribution profiles in forme fruste keratoconus and subclinical keratoconus. Cornea, 40(1): 61-72.

Toprak I, Cavas F, Velázquez JS, Alio Del Barrio JL, Alio JL (2020). Subclinical keratoconus detection with three-dimensional (3-D) morphogeometric and volumetric analysis. Acta Ophthalmologica, 98(8): e933-e942.

Toprak I (2020). Accelerated contact lens-assisted corneal collagen crosslinking and piggyback modification in a pediatric case with advanced keratoconus and thin cornea. Journal of Cataract & Refractive Surgery, 46(12): e35-e39.

Alió JL, Toprak I, Rodriguez A (2019). Treatment of severe keratoconus hydrops with intracameral platelet-rich plasma injection. Cornea, 38(12): 1595-1598.

Toprak I, Yaylali V, Yildirim C (2017). Visual, topographic and pachymetric effects of pediatric corneal collagen cross-linking. Journal of Pediatric Ophthalmology & Strabismus, 54(2): 84-89.

Toprak I, Yaylali V, Yildirim C (2015). A combination of topographic and pachymetric parameters in keratoconus diagnosis. Contact Lens & Anterior Eye, 38(5): 357-362.

Toprak I, Yaylali V, Yildirim C (2014). Factors affecting outcomes of corneal collagen crosslinking treatment. Eye (London), 28: 41-46.

Toprak I, Kucukatay V, Yildirim C, Kilic-Toprak E, Kilic-Erkek O (2014). Increased systemic oxidative stress in patients with keratoconus. Eye (London), 28(3): 285-289.

Toprak I, Yildirim C (2013). Scheimpflug parameters after corneal collagen crosslinking for keratoconus. European Journal of Ophthalmology, 23(6): 793-798.

Toprak I, Yildirim C (2013). Effects of corneal collagen crosslinking on corneal topographic indices in patients with keratoconus. Eye & Contact Lens, 39(6): 385-387.

Toprak I (2026). Predicting Early Keratoconus Progression Using Biomechanics via Multi-Machine Learning: A Multicenter 2-Year Prospective Cohort Study: Comment. Clinical & Experimental Ophthalmology, doi:10.1111/ceo.70157.

Toprak I, Parca O (2025). Comment on: Epithelial Mapping Efficacy for Subclinical Keratoconus Identification. American Journal of Ophthalmology, 276: 406-407.

Toprak I (2022). Comment on: Determining the Utility of Epithelial Thickness Mapping in Refractive Surgery Evaluations. American Journal of Ophthalmology, 241: 286-287.

Toprak I (2021). Comment on: Repeatability of the Pentacam HR in Various Grades of Keratoconus. American Journal of Ophthalmology, 225: 206.

Toprak I, Yaylali V (2019). Re: Hwang et al.: Distinguishing Highly Asymmetric Keratoconus Eyes Using Combined Scheimpflug and Spectral-Domain OCT Analysis. Ophthalmology, 126(7): e57-e58.

Toprak I, Yaylali V, Yildirim C (2014). Response to Vinciguerra et al. Eye (London), 28: 1033-1034.

Akkaya HS, Kilic-Toprak E, Cort A, Parca O, Toprak I (2026). Regenerative effects of RKI-1447 on human corneal endothelial cells: a comparative study. BMC Ophthalmology, 26(1): 504.

Kilic-Toprak E, Cort-Donmez A, Toprak I (2024). Effects of Autologous Serum and Platelet-Rich Plasma on Human Corneal Endothelial Cell Regeneration: A Comparative Study. Eye & Contact Lens, 50(2): 106-111.

Toprak I, Cetin EN, Gunes CE, Martin-Seker C (2021). Severe intraocular inflammation following hydrophilic acrylic phakic intraocular lens implantation in a case with concealed history of COVID-19: A case report and literature review. Ocular Immunology and Inflammation, 29(4): 662-665.

Fariselli C, Toprak I, Al-Shymali O, Alio Del Barrio JL, Alio JL (2020). Corneal transplantation outcomes after the extrusion of an intrastromal keratoprosthesis: a pilot study. Eye and Vision, 7: 26.

Toprak I, Fenkci SM, Fidan Yaylali G, Martin C, Yaylali V (2020). Early retinal neurodegeneration in preclinical diabetic retinopathy: a multifactorial investigation. Eye (London), 34(6): 1100-1107.

Toprak I, Fenkci SM, Fidan Yaylali G, Martin C, Yaylali V (2020). Effect of microalbuminuria on corneal endothelium in patients with diabetes without retinopathy. Clinical and Experimental Optometry, 103(5): 625-629.

Kilic-Toprak E, Toprak I, Caliskan S, Ozdemir Y, Demirtas O, Altintas F, Kucukatay V (2019). Oxidative Stress and Genotoxicity in Pterygium: A Systemic Investigation. Eye & Contact Lens, 45(6): 399-404.

Toprak I, Yaylali V (2019). "Crack, Reduce, and Implant": A Safe Phaco Technique in a Case with Hard Brown Cataract. Case Reports in Medicine, 2019: 9043417.

Toprak I, Yaylali V, Yildirim C (2017). Diagnostic consistency and relation between optical coherence tomography and standard automated perimetry in primary open angle glaucoma. Seminars in Ophthalmology, 32(2): 185-190.

Toprak I, Yaylali V, Yildirim C (2017). Early deterioration in ellipsoid zone in eyes with non-neovascular age-related macular degeneration. International Ophthalmology, 37(4): 801-806.

Toprak I, Yaylali V, Yildirim C (2016). Age-based analysis of choroidal thickness and choroidal vessel diameter in primary open-angle glaucoma. International Ophthalmology, 36(2): 171-177.

Kilic-Toprak E, Toprak I, Kilic-Erkek O, Kucukatay V, Bor-Kucukatay M (2016). Increased erythrocyte aggregation in patients with primary open angle glaucoma. Clinical and Experimental Optometry, 99(6): 544-549.

Toprak I, Yildirim C, Yaylali V (2015). Impaired photoreceptor inner segment ellipsoid layer reflectivity in mild diabetic retinopathy. Canadian Journal of Ophthalmology, 50(6): 438-441.

Demir C, Toprak I, Gungen S, Arslan A (2015). Lacrimal gland fistula following severe head trauma. Case Reports in Medicine, 2015: 1-2.

Yaylali V, Toprak I (2015). Exudative retinal detachment associated with complicated retrobulbar anesthesia. Open Journal of Ophthalmology, 5: 6-9.

Toprak I, Yaylali V, Yildirim C (2014). Decreased photoreceptor inner segment/outer segment junction reflectivity in patients with idiopathic epimacular membrane. Eye (London), 28: 1126-1130.

Toprak I, Yaylali V (2014). Bilateral cataract formation 25 years after indirect lightning injury. JCRS Online Case Reports, 2(1): e16-e17.

Toprak I, Yildirim C, Yaylali V (2012). Optic disc topographic analysis in diabetic patients. International Ophthalmology, 32: 559-564.

Toprak I, Kilic-Toprak E (2026). Letter Regarding: ESCALÓN: A Prospective Randomized Trial of Corneal Endothelial Cell Therapy in Subjects With Corneal Edema. Cornea, 45(9): e39-e40.

Toprak I (2020). Re: Patel et al.: Predicting the Prognosis of Fuchs Endothelial Corneal Dystrophy by Using Scheimpflug Tomography. Ophthalmology, 127(10): e88-e89.

Toprak I, Kilic D (2019). Using preoperative anterior segment optical coherence tomography to highly predict posterior capsule dehiscence in posterior polar cataract with simple image adjustments. Journal of Cataract & Refractive Surgery, 45(5): 704-705.

Toprak I, Martin C, Gunes CE, Alio J (2023). Revisiting Pentacam Parameters in the Diagnosis of Subclinical and Mild Keratoconus Based on Different Grading System Definitions. Turkish Journal of Ophthalmology, 53(6): 324-335.

Kilic D, Gunes CE, Toprak I (2023). Fuchs Endothelial Corneal Dystrophy and Keratoconus: A Very Rare Coincidence. Van Medical Journal, 30(3): 310-313.

Toprak I, Yildirim C, Yaylali V (2018). Comparison of anterior segment parameters in pediatric and adult keratoconus groups. Ege Journal of Medicine, 57: 19-25.

Toprak I, Kilic D (2023). The effects of the COVID-19 pandemic on paper participation in national ophthalmology meetings. Pamukkale Medical Journal, 16(4): 604-609.

Kilic D, Sirem MR, Aziz YN, Koca S, Toprak I (2023). Effect of Photochromic Senofilcon A Contact Lens on Total Aberrations of the Eye. Abant Medical Journal, 12: 98-104.

Toprak I, Tatlipinar S (2020). Retinal Detachment Due to Macular Hole and Posterior Breaks: Risk Factors, Pathogenesis, Clinical Features and Management. Güncel Retina, 4(3): 170-174.

Kilic-Toprak E, Toprak I, Yaylali V, Ozdemir Y, Oymak B, Bor-Kucukatay M, Kucukatay V (2019). Systemic Oxidant and Genotoxic Background in Exudative Age-Related Macular Degeneration. Süleyman Demirel University Journal of Health Sciences, 10(3): 273-277.

Kilic D, Dogan E, Toprak I (2019). Spontaneous Regression of Traumatic Macular Hole in a Pediatric Patient. Türkiye Klinikleri Journal of Ophthalmology, 28(4): 298-302.

Toprak I (2018). Long-term variability of peripapillary optical coherence tomography measurements in primary open-angle glaucoma. MN Ophthalmology, 25(1): 17-21.

Toprak I (2017). Comparison of the outcomes of primary pterygium surgery with suture versus fibrin glue-assisted autograft. MN Ophthalmology, 24(1): 9-12.

Toprak I, Yildirim C, Yaylali V (2016). Optical coherence tomography analysis of eyes with early glaucomatous visual field damage. Glaucoma-Cataract, 11: 100-104.

Toprak I (2016). Simultaneous presentation of classic choroidal neovascularization and diabetic retinopathy. Retina-Vitreus, 25: 265-268.

Toprak I, Demir C, Gungen S, Sari T (2015). Bilateral isolated sinopalpebral fistulas secondary to frontal sinusitis. Turkish Journal of Ophthalmology, 45: 84-85.

Toprak I (2014). Choroidal Micrometastasis as a First Manifestation of Systemic Involvement from Breast Cancer. Retina-Vitreus, 22: 302-304.

Acar M, Yaylali V, Cetin EN, Yildirim C, Demiryay Ozturk E, Toprak I, Avunduk AM (2011). Refractive surgery under topical anesthesia in anisometropic amblyopic children: two case reports. MN Ophthalmology, 18: 272-273.

Tatlipinar S, Toprak I (2008). Macular findings in nanophthalmos. MN Ophthalmology, 15: 209-210.

Tatlipinar S, Toprak I, Yildirim C, Yaylali V, Acar M, Ozden S (2007). Analysis of cases with central serous chorioretinopathy. Gülhane Medical Journal, 49: 213-215.

Alió JL, Toprak I, Alrabiah H (2022). Intraoperative Complications of LASIK and SMILE. In: Albert and Jakobiec's Principles and Practice of Ophthalmology (4th ed.). Springer International Publishing.

Alió JL, Toprak I (2020). The History of Femtosecond Laser Assisted LASIK (FS-LASIK). In: History of Refractive Surgery (Buratto L, Packard R, eds.). Fabiano Editoriale.

Toprak I (2024). Tips in Topographic Assessment Before Laser Refractive Surgery: A Step-by-Step Approach. In: Laser Refractive Surgery from Theory to Practice. Anadolu Kitabevi.

Yaylalı V, Toprak I (2022). Viral Conjunctivitis. In: Ocular Surface Diseases (Türk Oftalmoloji Derneği). Anadolu Kitabevi.

Toprak I (2021). Lens, Cataract and Refractive Surgery. In: MCQ for International Ophthalmology Board Exams-2. Anadolu Kitabevi.