Prof. Dr. Ziya Kalem

Образование и специализация

• Ondokuz Mayis University Faculty of Medicine — медицинское образование
• Ankara Dr. Zekai Tahir Burak Gynecology Hospital — специализация по акушерству и гинекологии
• Ankara IVF Center — подготовка по бесплодию и ЭКО

Профессиональные интересы

• ЭКО и вспомогательные репродуктивные технологии
• Диагностика женского и мужского бесплодия
• Лапароскопическая и гистероскопическая хирургия

Профессиональный опыт

• Ankara Sereflikochisar State Hospital — клиническая работа, 1993–1995
• Corum Maternity and Children’s Hospital — клиническая работа, 1996–2004
• Private Ankara IVF Center — клиническая работа, 2005–2006
• Частная больница Чорум — акушерство и гинекология, 2006–2012
• Gurgan Clinic IVF Center — медицинское руководство центром ЭКО, 2015–2019
• Istinye University Bahcesehir Liv Hospital IVF Center — клиническая работа, 2019–

Научная и профессиональная деятельность

• Национальные и международные публикации по репродуктивному здоровью, бесплодию и ЭКО

Избранные научные публикации

• Ziya Kalem, Müberra Namlı Kalem, Elvan Anado, Batuhan Bakırarar, Canan Yılmaz, Çiğdem Elmas, Perihan Yalçınkaya, Halil Ruso, Timur Gürgan. Maternal nutrition and reproductive functions of female and male offspring. Reproduction. 2018 Oct 1;156(4):353–364. DOI: 10.1530/REP-18-0070. PMID: 30306771.
• Ziya Kalem, Aski Ellibes Kaya, Batuhan Bakırarar, Alper Basbug, Müberra Namlı Kalem. An Optimal Uterine Closure Technique for Better Scar Healing and Avoiding Isthmocele in Cesarean Section: A Randomized Controlled Study. J Invest Surg. 2021 Feb;34(2):148-156. DOI: 10.1080/08941939.2019.1610530. PMID: 31070072.
• Ziya Kalem et al.. Intrauterine G-CSF Administration in Recurrent Implantation Failure (RIF): An Rct. Sci Rep. 2020 Mar 20;10(1):5139. DOI: 10.1038/s41598-020-61955-7. PMID: 32198409.
• Ziya Kalem, Müberra Namlı Kalem, Timur Gürgan. Methods for endometrial preparation in frozen-thawed embryo transfer cycles. J Turk Ger Gynecol Assoc. 2016 Sep 1;17(3):168-72. DOI: 10.5152/jtgga.2016.15214. PMID: 27651727.
• Ziya Kalem, Müberra Namlı Kalem, Batuhan Bakırarar, Erkin Kent, Timur Gurgan. Natural cycle versus hormone replacement therapy cycle in frozen-thawed embryo transfer. Saudi Med J. 2018 Nov;39(11):1102-1108 DOI: 10.15537/smj.2018.11.23299. PMID: 30397709.
• Ziya Kalem, Aşkı Ellibeş Kaya, Batuhan Bakırarar, Müberra Namlı Kalem. Fetal nuchal translucency: is there an association with birthweight and neonatal wellbeing?. Turk J Obstet Gynecol. 2019 Mar;16(1):35-40 DOI: 10.4274/tjod.galenos.2019.21384. PMID: 31019838.
• Timur Gürgan, Ziya Kalem, Müberra N Kalem, Halil Ruso, Moncef Benkhalifa, Antonis Makrigiannakis. Systematic and standardized hysteroscopic endometrial injury for treatment of recurrent implantation failure. Reprod Biomed Online. 2019 Sep;39(3):477-483. DOI: 10.1016/j.rbmo.2019.02.014. PMID: 31405721.
• İlknur Gümüş, Muberra Namli Kalem, Ziya Kalem, Onder Surgit, Aydın Köşüş. The Effect of Stress Incontinence Operations on Sexual Functions: Laparoscopic Burch versus Transvaginal Tape-O. Gynecol Minim Invasive Ther. 2018 Jul-Sep;7(3):108-113. DOI: 10.4103/GMIT.GMIT_22_18. PMID: 30254951.
• Muberra Namli Kalem, Ziya Kalem, Nilufer Akgun, Ebru Yuce, Hatice Aktas. Investigation of possible maternal and fetal factors which affect umbilical coiling index. J Matern Fetal Neonatal Med. 2019 Mar;32(6):954-960. DOI: 10.1080/14767058.2017.1396311. PMID: 29065736.
• Müberra Namlı Kalem, Ziya Kalem, Tuncay Yüce, Feride Soylemez. ADAMTS 1, 4, 12, and 13 levels in maternal blood, cord blood, and placenta in preeclampsia. Hypertens Pregnancy. 2018 Feb;37(1):9-17. DOI: 10.1080/10641955.2017.1397690. PMID: 29135310.
• Müberra Namlı Kalem, Ziya Kalem, Batuhan Bakırarar, Ali Ergün. The effect of progesterone use in the first trimester on fetal nuchal translucency. J Turk Ger Gynecol Assoc. 2018 Mar 01;19(1):29-33 DOI: 10.4274/jtgga.2017.0056. PMID: 29503259.
• Batuhan Bakirarar, Muberra Namli Kalem, Ziya Kalem. Factors that affect survival in vaginal cancer: a seer analysis. J Obstet Gynaecol. 2022 Aug DOI: 10.1080/01443615.2022.2049717. PMID: 35543117.
• Müberra Namlı Kalem, Ziya Kalem, Tuncay Yuce, Batuhan Bakırarar, Feride Söylemez. Comparison of Melatonin Levels in the Colostrum between Vaginal Delivery and Cesarean Delivery. Am J Perinatol. 2018 Apr;35(5):481-485. DOI: 10.1055/s-0037-1608681. PMID: 29166676.
• Müberra Namlı Kalem, Ziya Kalem, Ebru Yüce, Ayla Eser, Zehra Candan İltemir Duvan. Problems of modern approaches to management of early pregnancy failure. Turk J Obstet Gynecol. 2015 Dec;12(4):230-236. DOI: 10.4274/tjod.79059. PMID: 28913075.
• Turgut Aydin, Muberra Namli Kalem, Batuhan Bakirarar, Elif Ganime Aygun, Ziya Kalem. Comparing the success rate of natural cycle and modified natural cycle protocols for frozen-thawed embryo transfer. Gynecol Endocrinol. 2022 Dec;38(12):1073-1078. DOI: 10.1080/09513590.2022.2128747. PMID: 36220075.
• Müberra Namlı Kalem, Ziya Kalem, Tamer Sarı, Can Ateş, Timur Gürgan. Effect of body mass index and age on in vitro fertilization in polycystic ovary syndrome. J Turk Ger Gynecol Assoc. 2016;17(2):83-90 DOI: 10.5152/jtgga.2016.15235. PMID: 27403074.
• Ziya Kalem, Muberra Namli Kalem, Halil Ruso, Batuhan Bakirarar, Timur Gurgan. Fresh versus frozen-thawed blastocyst transfer in high responders. Ginekol Pol. 2018;89(8):407-413 DOI: 10.5603/GP.a2018.0070. PMID: 30215458.
• Muberra Namlı Kalem, Ziya Kalem, Nilufer Akgun, Batuhan Bakırarar. The relationship between postmenopausal women's sclerostin levels and their bone density, age, body mass index, hormonal status, and smoking and consumption of coffee and dairy products. Arch Gynecol Obstet. 2017 Mar;295(3):785-793 DOI: 10.1007/s00404-017-4288-x. PMID: 28138749.
• Muberra Namlı Kalem, Elvan Anadol, Ziya Kalem, Perihan Yalçınkaya Sezginer, Cigdem Elmas, Canan Yılmaz, Batuhan Bakirarar. A rat study on the PTEN expression in ovarian tissue in PCOS and folliculogenesis. Sci Rep. 2023 11 26;13(1):20774 DOI: 10.1038/s41598-023-47809-y. PMID: 38008769.
• Muberra Namli Kalem, Aydın Köşüş, Zeynep Kamalak, Nermin Köşüş, Ziya Kalem. Factors affecting the rates of caesarean sections in cases with premature rupture of membranes (PROM) at term. J Obstet Gynaecol. 2017 Jul;37(5):585-590. DOI: 10.1080/01443615.2016.1274291. PMID: 28285555.
• Müberra Namli Kalem, Ziya Kalem, Batuhan Bakirarar, Kadir Demircan. Adamts 1, 4, 5, 8, and 9 in Early Pregnancies. Fetal Pediatr Pathol. 2017 Oct;36(5):387-399 DOI: 10.1080/15513815.2017.1354410. PMID: 28949770.
• Müberra Namlı Kalem, Nilufer Akgun, Ziya Kalem, Batuhan Bakirarar, Tugrul Celik. Chemokine (C-C motif) ligand-2 (CCL2) and oxidative stress markers in recurrent pregnancy loss and repeated implantation failure. J Assist Reprod Genet. 2017 Nov;34(11):1501-1506. DOI: 10.1007/s10815-017-0992-5. PMID: 28707148.
• Nilufer Akgun, Muberra Namli Kalem, Ebru Yuce, Ziya Kalem, Hatice Aktas. Correlations of maternal neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) with birth weight. J Matern Fetal Neonatal Med. 2017 Sep;30(17):2086-2091 DOI: 10.1080/14767058.2016.1237497. PMID: 27678153.
• Nafiye Yılmaz, Banu Seven, Hakan Timur, Ayçağ Yorgancı, Hasan Ali İnal, Müberra Namlı Kalem, Ziya Kalem, Özge Han, Banu Bilezikçi. Reply. J Chin Med Assoc. 2018 11;81(11):1015 DOI: 10.1016/j.jcma.2018.07.003. PMID: 30201190.
• Melahat Atasever, Müberra Namlı Kalem, Şafak Hatırnaz, Ebru Hatırnaz, Ziya Kalem, Zeynep Kalaylıoğlu. Factors affecting clinical pregnancy rates after IUI for the treatment of unexplained infertility and mild male subfertility. J Turk Ger Gynecol Assoc. 2016;17(3):134-8 DOI: 10.5152/jtgga.2016.16056. PMID: 27651720.
• Enhancement of Folliculogenesis by Fresh Onion Juice in a Rat Model. Current Traditional Medicine. 2021.
• Rewarding Conversation Between Oocyte and Cumulus Cells Directs the Process of Folliculogenesis. 2019.

Доклады на научных конференциях

• Namlı Kalem M, Kalem Z, Seval M, Yılmaz C, Atabekoğlu CS. Is Stem Cell Factor Concentration of Follicular Fluid in Polycystic Ovarian Syndrome Effective on IVF/ICSI Outcome?
• Namlı Kalem M, Kalem Z, Akgün N, Bakırarar B. The Relationship Between the Levels of Anti-Müllerian Hormone, Vaspin, and Visfatin and the Patterns of Nutrition and Menstruation in Non-Polycystic Ovary Syndrome and Non-Obese Young Women.
• Kalem Z, Kocabaş MI, Namlı Kalem M, Bakırarar B, Gürgan T. The Effect of Granulocyte Colony Stimulating Factor Infusion into the Endometrial Cavity on IVF Outcome in Women with Recurrent Implantation Failure.