Prof. Dr. Dilek Karakaya

Образование и специализация

• Стамбульский медицинский факультет Стамбульского университета — медицинское образование
• Стамбульский медицинский факультет — специализация по внутренним болезням
• Учебно-исследовательская больница Atatürk — субспециализация по эндокринологии и болезням обмена веществ

Профессиональный опыт

• Medical Park Gebze — эндокринология и болезни обмена веществ

Клинические интересы

• Сахарный диабет
• Заболевания щитовидной железы
• Заболевания паращитовидных желёз
• Заболевания гипофиза
• Остеопороз
• Ожирение

Профессиональное членство

• Турецкое общество эндокринологии и метаболизма
• European Society of Endocrinology

Проверенные библиографические записи

1. Aktaş T, Celik SK, Genc GC, Arpaci D, Can M, Dursun A. Higher Levels of Serum TLR2 and TLR4 in Patients with Hashimoto's Thyroiditis. Endocr Metab Immune Disord Drug Targets. 2020;20(1):118-126. doi: 10.2174/1871530319666190329114621. PMID: 30924423.
2. Arpaci D, Ozdemir D, Cuhaci N, Kiyak G, Yalcin A, Akbaba S, Kilicyazgan A, Ersoy R, Cakir B. Do repeatedly nondiagnostic fine needle aspirations of thyroid nodules predict malignancy risk? Ann Diagn Pathol. 2014 Oct;18(5):297-300. doi: 10.1016/j.anndiagpath.2014.08.005. Epub 2014 Aug 16. PMID: 25171877.
3. Arpaci D, Gurol G, Ergenc H, Yazar H, Tocoglu AG, Ciftci IH, Tamer A. A Controversial New Approach to Address Hematological Parameters in Hashimoto's Thyroiditis. Clin Lab. 2016 Jul 1;62(7):1225-1231. doi: 10.7754/Clin.Lab.2015.150927. PMID: 28164629.
4. Kuzu F, Arpaci D, Unal M, Altas A, Haytaoglu G, Can M, Barut F, Kokturk F, Ilikhan SU, Bayraktaroglu T. Midkine: A Novel Biomarker to Predict Malignancy in Patients with Nodular Thyroid Disease. Int J Endocrinol. 2016;2016:6035024. doi: 10.1155/2016/6035024. Epub 2016 Jun 30. PMID: 27446208.
5. Arpaci D, Kuzu F, Unal M, Ilikhan SU, Buyukuysal MC, Bayraktaroglu T. Assessment of Mean Platelet Volume and its Effect on Disease Control in Patients with Acromegaly. Clin Lab. 2016 Nov 1;62(11):2167-2171. doi: 10.7754/Clin.Lab.2016.160404. PMID: 28164675.
6. Arpaci D, Ugurlu BP, Aslan AN, Ersoy R, Akcay M, Cakir B. Epicardial fat thickness in patients with prediabetes and correlation with other cardiovascular risk markers. Intern Med. 2015;54(9):1009-14. doi: 10.2169/internalmedicine.54.3714. Epub 2015 May 1. PMID: 25948339.
7. Emre A, Karadeniz Cakmak G, Karakaya Arpaci D, Uygun Ilikhan S, Damar M. The Efficacy of Intraoperative Single Dose Methylprednisolone on Recurrent Laryngeal Nerve Function After Thyroidectomy. Int Surg. 2016 Mar 23. doi: 10.9738/INTSURG-D-15-00222.1. Online ahead of print. PMID: 27007178.
8. Kuzu F, Arpaci D, Acar FZ, Tikanak SP, Cakmak GK, Celebi G, Comert FS, Uygun SI, Bayraktaroglu T. A case of suppurative thyroiditis caused by Salmonella presented with thyrotoxicosis. Indian J Med Microbiol. 2016 Apr-Jun;34(2):266-7. doi: 10.4103/0255-0857.177405. PMID: 27080802.
9. Yazgan S, Arpaci D, Celik HU, Isik I. Evaluation of macular and peripapillary choroidal thickness, macular volume and retinal nerve fiber layer in acromegaly patients. Int Ophthalmol. 2018 Apr;38(2):617-625. doi: 10.1007/s10792-017-0500-z. Epub 2017 May 15. PMID: 28508245.
10. Demirseren DD, Emre S, Akoglu G, Arpacı D, Arman A, Metin A, Cakır B. Relationship between skin diseases and extracutaneous complications of diabetes mellitus: clinical analysis of 750 patients. Am J Clin Dermatol. 2014 Feb;15(1):65-70. doi: 10.1007/s40257-013-0048-2. PMID: 24135944.
11. Arpaci D, Karakas Celik S, Can M, Ermiş E, Kuzu F, Kokturk F, Hamamcioglu AC, Dursun A, Bayraktaroglu T. Serum paraoxonase level and paraoxonase polymorphism in patients with acromegaly. Redox Rep. 2016 Nov;21(6):281-6. doi: 10.1080/13510002.2015.1133036. Epub 2016 Feb 15. PMID: 26863932.
12. Altas A, Kuzu F, Arpaci D, Unal M, Can M, Barut F, Kokturk F, Ilikhan SU, Bayraktaroglu T. The Clinical Values of Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 Levels in Blood and Thyroid Nodules. Int J Endocrinol. 2017;2017:3145234. doi: 10.1155/2017/3145234. Epub 2017 Sep 7. PMID: 29081797.
13. Yazgan S, Arpaci D, Celik HU, Dogan M, Isık I. Macular Choroidal Thickness May Be the Earliest Determiner to Detect the Onset of Diabetic Retinopathy in Patients with Prediabetes: A Prospective and Comparative Study. Curr Eye Res. 2017 Jul;42(7):1039-1047. doi: 10.1080/02713683.2016.1264606. Epub 2017 Jan 25. PMID: 28121176.
14. Kuzu F, Arpaci D, Cakmak GK, Emre AU, Elri T, Ilikhan SU, Bahadir B, Bayraktaoglu T. Focused parathyroidectomy without intra-operative parathormone monitoring: The value of PTH assay in preoperative ultrasound guided fine needle aspiration washout. Ann Med Surg (Lond). 2016 Feb 8;6:64-7. doi: 10.1016/j.amsu.2015.12.065. eCollection 2016 Mar. PMID: 26955476.
15. Arpaci D, Karakece E, Tocoglu AG, Ergenc H, Gurol G, Ciftci IH, Tamer A. Endocan, TGF-beta, and ADMA as Risk Factors for Endothelial Dysfunction and Possible Vascular Disease in Patients with Subclinical Hypothyroidism. Ann Clin Lab Sci. 2016 Dec;46(6):601-607. PMID: 27993872.
16. Arpaci D, Saglam F, Cuhaci FN, Ozdemir D, Ersoy R, Cakir B. Serum testosterone does not affect bone mineral density in postmenopausal women. Arch Endocrinol Metab. 2015 Aug;59(4):292-6. doi: 10.1590/2359-3997000000085. PMID: 26331315.
17. Arpaci D, Gurkan Tocoglu A, Yilmaz S, Korkmaz S, Ergenc H, Gunduz H, Keser N, Tamer A. Epicardial Adipose Tissue Thickness in Patients With Subclinical Hypothyroidism and the Relationship Thereof With Visceral Adipose Tissue Thickness. J Clin Med Res. 2016 Mar;8(3):215-9. doi: 10.14740/jocmr2460w. Epub 2016 Jan 26. PMID: 26858794.
18. Arpaci D, Gurkan Tocoglu A, Yilmaz S, Ergenc H, Tamer A, Keser N, Gunduz H. The relationship between epicardial fat tissue thickness and visceral adipose tissue in lean patients with polycystic ovary syndrome. J Ovarian Res. 2015 Nov 6;8:71. doi: 10.1186/s13048-015-0197-4. PMID: 26545735.
19. Arpaci D, Karakas Celik S, Can M, Cakmak Genc G, Kuzu F, Unal M, Bayraktaroglu T. Increased Serum Levels of IL-28 and IL-29 and the Protective Effect of IL28B rs8099917 Polymorphism in Patients with Hashimoto's Thyroiditis. Immunol Invest. 2016 Oct;45(7):668-78. doi: 10.1080/08820139.2016.1208215. Epub 2016 Sep 12. PMID: 27617784.
20. Yavuz DG, Bilen H, Sancak S, Garip T, Hekimsoy Z, Sahin I, Yilmaz M, Aydin H, Atmaca A, Sert M, Karakaya P, Arpaci D, Oguz A, Guvener N. Impact of telephonic interviews on persistence and daily adherence to insulin treatment in insulin-naïve type 2 diabetes patients: dropout study. Patient Prefer Adherence. 2016 May 17;10:851-61. doi: 10.2147/PPA.S100626. eCollection 2016. PMID: 27274207.
21. Haytaoglu G, Kuzu F, Arpaci D, Altas A, Can M, Barut F, Kokturk F, Ilikhan SU, Bayraktaroglu T. Correlation of vascular endothelial growth factor and vascular endothelial growth factor receptor-1 levels in serum and thyroid nodules with histopathological and radiological variables. J Lab Physicians. 2019 Jan-Mar;11(1):51-57. doi: 10.4103/JLP.JLP_41_18. PMID: 30983803.
22. Arpaci D, Ozdemir D, Cuhaci N, Dirikoc A, Kilicyazgan A, Guler G, Ersoy R, Cakir B. Evaluation of cytopathological findings in thyroid nodules with macrocalcification: macrocalcification is not innocent as it seems. Arq Bras Endocrinol Metabol. 2014 Dec;58(9):939-45. doi: 10.1590/0004-2730000003602. PMID: 25627050.
23. Oz II, Bilici M, Serifoglu I, Karakaya Arpaci D, Buyukuysal MC, Bayraktaroglu T. ASSOCIATION OF PANCREAS VOLUME AND INSULIN RESISTANCE WITH ABDOMINAL FAT DISTRIBUTION IN TYPE-2 DIABETES AS EVALUATED BY COMPUTED TOMOGRAPHY. Acta Endocrinol (Buchar). 2017 Apr-Jun;13(2):168-173. doi: 10.4183/aeb.2017.168. PMID: 31149169.
24. Çuhaci N, Arpaci D, Üçler R, Yazgan AK, Kıyak G, Yalçin S, Ersoy PE, Güler G, Ersoy R, Çakir B. Malignancy rate of thyroid nodules defined as follicular lesion of undetermined significance and atypia of undetermined significance in thyroid cytopathology and its relation with ultrasonographic features. Endocr Pathol. 2014 Sep;25(3):248-56. doi: 10.1007/s12022-014-9298-7. PMID: 24532158.
25. Ozdemir D, Arpaci D, Ucler R, Cuhaci N, Ersoy R, Cakir B. Parathyroid incidentalomas detected during thyroid ultrasonography and effect of chronic thyroiditis on false positive parathyroid lesions. Endocrine. 2012 Dec;42(3):616-21. doi: 10.1007/s12020-012-9700-5. Epub 2012 May 23. PMID: 22618378.
26. Gozdas HT, Arpaci D. Age, gender & co-morbidities as risk factors for drug-induced diseases. Indian J Med Res. 2015 Nov;142(5):618. doi: 10.4103/0971-5916.171297. PMID: 26658600.
27. Ozdemir D, Ersoy R, Cuhaci N, Arpaci D, Ersoy EP, Korukluoglu B, Guler G, Cakir B. Classical and follicular variant papillary thyroid carcinoma: comparison of clinical, ultrasonographical, cytological, and histopathological features in 444 patients. Endocr Pathol. 2011 Jun;22(2):58-65. doi: 10.1007/s12022-011-9160-0. PMID: 21556739.
28. Cuhaci N, Ozdemir D, Polat B, Arpacı D, Yıldırım N, Yazgan AK, Yalcın S, Kılıc M, Ersoy R, Cakir B. Concomitant thyroid lesions in patients with primary hyperparathyroidism. Asian J Surg. 2017 Sep;40(5):338-344. doi: 10.1016/j.asjsur.2015.10.006. Epub 2016 Jan 11. PMID: 26786663.
29. Arpaci D, Demir MV, Garip T, Tamer A. A Case of QT Prolongation Associated with Panhypopituitarism. Case Rep Endocrinol. 2013;2013:989745. doi: 10.1155/2013/989745. Epub 2013 May 9. PMID: 23762665.
30. Ozturk S, Arpaci D, Yazici H, Taymez DG, Aysuna N, Yildiz A, Sever MS. Outcomes of acute renal failure patients requiring intermittent hemodialysis. Ren Fail. 2007;29(8):991-6. doi: 10.1080/08860220701641819. PMID: 18067046.