Formation et spécialisation

• Faculté de médecine Cerrahpaşa de l’Université d’Istanbul — études de médecine
• Faculté de médecine Cerrahpaşa de l’Université d’Istanbul — spécialisation en médecine interne
• Hôpital de formation et de recherche Türkiye Yüksek İhtisas — gastro-entérologie
• Titre de professeur associé en gastro-entérologie (2013)

Domaines d’expertise

• Maladies du foie
• Hépatite C
• Hépatite B
• Endoscopie
• CPRE (ERCP)
• Maladies inflammatoires de l’intestin

Distinctions

• Deuxième place en Türkiye au 5e examen de qualification de la Société turque de médecine interne (2006)
• Diplôme européen de médecine interne, European Board of Internal Medicine (2007)
• Première place en Türkiye en médecine interne à l’examen d’entrée en surspécialité médicale (YDUS) (2008)
• Certificat de réussite à l’examen national de qualification de la Société turque de gastro-entérologie (2012)

Publications scientifiques

• Kekilli M, Tanoğlu A, Karaahmet F, Doğan Z, Can M, Sayilir A, Çakal B, Düzenli T, Beyazit Y. Midkine level may be used as a noninvasive biomarker in Crohn’s disease. Turk J Med Sci. 2020;50(2):324-329. doi:10.3906/sag-1904-167. PMID:31905498.
• Beyazit Y, Sayilir A, Tanoglu A, Kekilli M, Kocak E, Ekiz F, Tas A. Plasma Thrombin-activatable Fibrinolysis Inhibitor Levels Correlate with the Disease Activity of Ulcerative Colitis. Intern Med. 2016;55(14):1831-6. doi:10.2169/internalmedicine.55.6473. PMID:27432089.
• Basaranoglu M, Sayilir A, Demirbag AE, Mathew S, Ala A, Senturk H. Seasonal clustering in inflammatory bowel disease: a single centre experience. Expert Rev Gastroenterol Hepatol. 2015;9(6):877-81. doi:10.1586/17474124.2015.1025054. PMID:25790731.
• Tanoglu A, Balta AZ, Berber U, Ozdemir Y, Emirzeoglu L, Sayilir A, Sucullu I. MicroRNA expression profile in patients with stage II colorectal cancer: a Turkish referral center study. Asian Pac J Cancer Prev. 2015;16(5):1851-5. doi:10.7314/apjcp.2015.16.5.1851. PMID:25773836.
• Beyazit Y, Efe C, Tanoglu A, Purnak T, Sayilir A, Taskıran I, Kekilli M, Turhan T. Nitric oxide is a potential mediator of hepatic inflammation and fibrogenesis in autoimmune hepatitis. Scand J Gastroenterol. 2015;50(2):204-10. doi:10.3109/00365521.2014.974203. PMID:25495215.
• Kurt M, Oguz D, Oztas E, Kalkan IH, Sayilir A, Beyazit Y, Sasmaz N. Safety of endoscopic ultrasonography in elderly patients: a single center prospective trial. Aging Clin Exp Res. 2013;25(5):571-4. doi:10.1007/s40520-013-0138-2. PMID:24026626.
• Köksal AS, Onder FO, Torun S, Parlak E, Sayilir A, Tayfur O, Yildiz H, Ozbalci GS, Kayaçetin E. Twice a day quadruple therapy for the first-line treatment of Helicobacter pylori in an area with a high prevalence of background antibiotic resistance. Acta Gastroenterol Belg. 2013;76(1):34-7. PMID:23650780.
• Kekilli M, Beyazit Y, Tas A, Tunc B, Sayilir A, Ulker A. Atypical pANCA as a marker of indeterminate colitis for the prediction of ulcerative colitis and Crohn's disease. Wien Klin Wochenschr. 2013;125(9-10):279-82. doi:10.1007/s00508-013-0363-x. PMID:23619641.
• Suvak B, Torun S, Yildiz H, Sayilir A, Yesil Y, Tas A, Beyazit Y, Sasmaz N, Kayaçetin E. Mean platelet volume is a useful indicator of systemic inflammation in cirrhotic patients with ascitic fluid infection. Ann Hepatol. 2013;12(2):294-300. PMID:23396741.
• Beyazit Y, Sayilir A, Koklu S, Torun S, Suvak B, Tas A, Purnak T, Kalkan IH, Yesil Y, Ibis M. Serum nitric oxide levels in patients with benign and malignant biliary disease: a prospective single center study. J Clin Gastroenterol. 2013;47(3):258-63. doi:10.1097/MCG.0b013e318263ccd1. PMID:23059408.
• Purnak T, Olmez S, Torun S, Efe C, Sayilir A, Ozaslan E, Tenlik I, Kalkan IH, Beyazit Y, Yuksel O. Mean platelet volume is increased in chronic hepatitis C patients with advanced fibrosis. Clin Res Hepatol Gastroenterol. 2013;37(1):41-6. doi:10.1016/j.clinre.2012.03.035. PMID:22572524.
• Beyazit Y, Sayilir A, Suvak B, Torun S, Haznedaroglu IC. Molecular basis of Ankaferd-induced hemostasis in the management of sternal bleeding. Heart Surg Forum. 2012;15(6):E305. doi:10.1532/HSF98.20111010. PMID:23262043.
• Önal İK, Beyazit Y, Şener B, Savuk B, Etık DÖ, Sayilir A, Öztaş E, Torun S, Özın YÖ, Demırel BT, Ülker A, Dağli Ü. The value of fecal calprotectin as a marker of intestinal inflammation in patients with ulcerative colitis. Turk J Gastroenterol. 2012;23(5):509-14. doi:10.4318/tjg.2012.0421. PMID:23161295.
• Kalkan IH, Etik DÖ, Oztaş E, Sayilir A, Dişibeyaz S, Kuran SÖ. A rare cause of upper GI hemorrhage: an uncorrupted sponge migrating into the duodenal bulb (with video). Gastrointest Endosc. 2012;76(6):1246. doi:10.1016/j.gie.2012.07.027. PMID:22998836.
• Torun S, Tunc BD, Suvak B, Yildiz H, Tas A, Sayilir A, Ozderin YO, Beyazit Y, Kayacetin E. Assessment of neutrophil-lymphocyte ratio in ulcerative colitis: a promising marker in predicting disease severity. Clin Res Hepatol Gastroenterol. 2012;36(5):491-7. doi:10.1016/j.clinre.2012.06.004. PMID:22841412.
• Onal IK, Akdogan M, Arhan M, Yalinkilic ZM, Cicek B, Kacar S, Kurt M, Ibis M, Ozin YO, Sayilir A, Sasmaz N. Double balloon enteroscopy: a 3-year experience at a tertiary care center. Hepatogastroenterology. 2012;59(118):1851-4. doi:10.5754/hge10828. PMID:22819903.
• Ibiş M, Beyazit Y, Turokoğlu MA, Celep B, Sayilir A, Suvak B, Kekilli M. Successful endoscopic management of anastomotic dehiscence with hemoclips application after pancreaticoduodenectomy. Turk J Gastroenterol. 2012;23(3):301-2. doi:10.4318/tjg.2012.0361. PMID:22798125.
• Sayilir A, Ödemis B, Köksal AS, Beyazit Y, Kayacetin E. Image of the month: Fasciola hepatica as a cause of cholangitis. Am J Gastroenterol. 2012;107(5):655. PMID:22696768.
• Kurt M, Onal IK, Sayilir AY, Beyazit Y, Oztas E, Kekilli M, Turhan N, Karaman K, Akdogan M. The role of mean platelet volume in the diagnosis of hepatocellular carcinoma in patients with chronic liver disease. Hepatogastroenterology. 2012;59(117):1580-2. doi:10.5754/hge10444. PMID:22683976.
• Beyazit Y, Kekilli M, Ibis M, Kurt M, Sayilir A, Onal IK, Purnak T, Oztas E, Tas A, Yesil Y, Arhan M. Can red cell distribution width help to discriminate benign from malignant biliary obstruction? A retrospective single center analysis. Hepatogastroenterology. 2012;59(117):1469-73. doi:10.5754/hge10676. PMID:22683963.
• Kekilli M, Beyazit Y, Karaman K, Sayilir A, Kurt M, Onal IK, Yesil Y, Akdogan M, Sasmaz N. Endoscopic and pathological aspects of gastric polyps: a Turkish referral center study. Hepatogastroenterology. 2012;59(116):1147-9. doi:10.5754/hge10785. PMID:22580668.
• Albayrak M, Celebi H, Albayrak A, Sayilir A, Yesil Y, Balcik OS, Yokus O, Celik T. Elevated serum angiotensin converting enzyme levels as a reflection of bone marrow renin-angiotensin system activation in multiple myeloma. J Renin Angiotensin Aldosterone Syst. 2012;13(2):259-64. doi:10.1177/1470320312437070. PMID:22345095.
• Beyazit Y, Koklu S, Tas A, Purnak T, Sayilir A, Kurt M, Turhan T, Celik T, Suvak B, Torun S, Akbal E. Serum adenosine deaminase activity as a predictor of disease severity in ulcerative colitis. J Crohns Colitis. 2012;6(1):102-7. doi:10.1016/j.crohns.2011.07.010. PMID:22261534.
• Sayilir A, Beyazit Y, Yesil Y, Albayrak M, Ekiz F, Celik T, Suvak B, Torun S, Ibiş M. Plasma thrombin-activatable fibrinolysis inhibitor as an indicator of inflammation and disease severity in acute pancreatitis. Clin Res Hepatol Gastroenterol. 2012;36(5):498-504. doi:10.1016/j.clinre.2011.12.006. PMID:22230218.
• Taş A, Köklü S, Beyazit Y, Kurt M, Sayilir A, Yeşil Y, Çelik H. Thyroid hormone levels predict mortality in intensive care patients with cirrhosis. Am J Med Sci. 2012;344(3):175-9. doi:10.1097/MAJ.0b013e318239a666. PMID:22143128.
• Beyazit Y, Sayilir A, Torun S, Suvak B, Yesil Y, Purnak T, Oztas E, Kurt M, Kekilli M, Ibis M. Mean platelet volume as an indicator of disease severity in patients with acute pancreatitis. Clin Res Hepatol Gastroenterol. 2012;36(2):162-8. doi:10.1016/j.clinre.2011.10.003. PMID:22088974.
• Sayilir A, Kekıllı M, Arhan M, Beyazit Y, Celep B, Saşmaz N. Abdominal tuberculosis mimicking gastric submucosal tumor. Turk J Gastroenterol. 2011;22(6):654-5. doi:10.4318/tjg.2011.0314. PMID:22287420.
• Suvak B, Beyazit Y, Sayilir A, Kurt M, Kekilli M. An unusual local complication of endoscopic nasobiliary drain catheter placement. Gastroenterol Nurs. 2011;34(6):470-1. doi:10.1097/SGA.0b013e31823994fa. PMID:22129800.
• Beyazit Y, Kurt M, Sayilir A, Suvak B, Ozderin YO. Successful application of ankaferd blood stopper in a patient with lower gastrointestinal bleeding. Saudi J Gastroenterol. 2011;17(6):424-5. doi:10.4103/1319-3767.87189. PMID:22064346.
• Sayilir A, Onal IK, Beyazit Y, Surmelioğlu A, Okten RS, Odemis B, Parlak E, Sasmaz N. A rare cause of upper gastrointestinal bleeding: hemosuccus pancreaticus: angiographic and endoscopic combined treatment. Surg Laparosc Endosc Percutan Tech. 2011;21(5):e286-7. doi:10.1097/SLE.0b013e31822f50b6. PMID:22002298.
• Sayilir A, Kurt M, Onal IK, Beyazit Y, Suvak B. An unusual complication of peptic ulcer disease: double pylorus. Gastroenterol Nurs. 2011;34(5):401-2. doi:10.1097/SGA.0b013e31822c69f9. PMID:21979403.
• Sayilir A, Oztaş E, Onal IK, Kurt M, Kekıllı M, Akdoğ G, Ibış M. Small bowel obstruction: a presenting symptom of squamous cell carcinoma of the lung. Turk J Gastroenterol. 2011;22(4):440-2. doi:10.4318/tjg.2011.0292. PMID:21948581.
• Beyazit Y, Purnak T, Suvak B, Kurt M, Sayilir A, Turhan T, Tas A, Torun S, Celik T, Ibis M, Haznedaroglu IC. Increased ACE in extrahepatic cholangiocarcinoma as a clue for activated RAS in biliary neoplasms. Clin Res Hepatol Gastroenterol. 2011;35(10):644-9. doi:10.1016/j.clinre.2011.06.008. PMID:21802387.
• Öztaş E, Parlak E, Sayilir A, Dağli Ü, Arhan M, Etık D, Ülker A. Visible common bile duct at the duodenum due to the destructive effect of the tumor. Turk J Gastroenterol. 2011;22(2):231. PMID:21796570.
• Suvak B, Beyazit Y, Sayilir A, Torun S, Suvak O. Effects of corticosteroid therapy on depression and inflammation in ulcerative colitis patients. J Crohns Colitis. 2011;5(4):375-6; author reply 377. doi:10.1016/j.crohns.2011.04.001. PMID:21683313.
• Oztas E, Oguz D, Kurt M, Etik DO, Cicek B, Kekilli M, Onal IK, Sayilir A, Kacar S, Sahin B. Endosonographic evaluation of patients with suspected extraluminal compression or subepithelial lesions during upper gastrointestinal endoscopy. Eur J Gastroenterol Hepatol. 2011;23(7):586-92. doi:10.1097/MEG.0b013e3283461045. PMID:21654261.
• Beyazit Y, Sayilir A, Suvak B, Torun S. The missing link between obesity and hepatocellular carcinoma: IL-6-mediated STAT-3 activation as a key player in hepatocarcinogenesis. Digestion. 2011;84(3):185-6. doi:10.1159/000327908. PMID:21625138.
• Sayilir A, Kurt M, Kekilli M, Onal IK, Beyazit Y, Turhan N, Ibiş M, Arhan M. Diagnostic value of terminal ileum biopsy in chronic diarrhea with normal endoscopic appearance. J Dig Dis. 2011;12(3):188-92. doi:10.1111/j.1751-2980.2011.00503.x. PMID:21615872.
• Ibis M, Beyazit Y, Sayilir A, Suvak B, Torun S, Kekilli M. Successful treatment of eosinophilic colitis by montelukast sodium plus budesonide in a patient with Waldenstrom macroglobulinemia. J Crohns Colitis. 2011;5(3):277-8. doi:10.1016/j.crohns.2011.03.008. PMID:21575902.
• Beyazit Y, Sayilir A, Suvak B, Kekilli M, Tas A. Comment on: Use of Ankaferd Blood Stopper for controlling actively bleeding fundal varices. Singapore Med J. 2011;52(4):317-8. PMID:21552796.
• Beyazit Y, Kekilli M, Kurt M, Sayilir A, Haznedaroglu IC. Ankaferd hemostat for the management of tumoral GI bleeding. Gastrointest Endosc. 2011;73(5):1072-3. doi:10.1016/j.gie.2010.11.045. PMID:21521581.
• Beyazit Y, Sayilir A, Kekilli M, Kurt M, Gorgulu O. Phosphoinositide-3-kinase inhibition with theophylline reverses steroid insensitivity in acute alcoholic hepatitis. Med Hypotheses. 2011;77(1):157. doi:10.1016/j.mehy.2011.03.031. PMID:21482031.
• Beyazit Y, Ibis M, Purnak T, Turhan T, Kekilli M, Kurt M, Sayilir A, Onal IK, Turhan N, Tas A, Köklü S, Haznedaroglu IC. Elevated levels of circulating angiotensin converting enzyme in patients with hepatoportal sclerosis. Dig Dis Sci. 2011;56(7):2160-5. doi:10.1007/s10620-011-1580-7. PMID:21290180.
• Kurt M, Akdogan M, Sayilir A, Kuran S, Ozderin YO, Arhan M, Onal IK, Kekilli M, Beyazit Y, Hayran M. Effect of endoscopic injection therapy with combined cyanoacrylate and lipiodol for bleeding gastric varices: A single center experience. J Dig Dis. 2010;11(5):284-90. doi:10.1111/j.1751-2980.2010.00451.x. PMID:20883424.
• Beyazit Y, Sayilir A, Tas A, Kekilli M. IgA and IgG antibody testing for coeliac disease. Eur J Intern Med. 2010;21(5):467-8; author reply 468. doi:10.1016/j.ejim.2010.05.013. PMID:20816608.
• Kurt M, Onal I, Akdogan M, Kekilli M, Arhan M, Sayilir A, Oztas E, Haznedaroglu I. Ankaferd Blood Stopper for controlling gastrointestinal bleeding due to distinct benign lesions refractory to conventional antihemorrhagic measures. Can J Gastroenterol. 2010;24(6):380-4. doi:10.1155/2010/896819. PMID:20559581.
• Sayilir A, Kekilli M, Kurt M, Onal IK, Yesil Y, Tunc B, Sasmaz N. An ethical dilemma: decision making about liver transplantation in a patient with schizophrenia. Gastroenterol Nurs. 2010;33(1):59-60. doi:10.1097/SGA.0b013e3181ce3bd2. PMID:20145454.
• Sayilir A, Kurt M, Ibis M, Kekilli M, Onal IK, Sasmaz N. Transient global amnesia following upper gastrointestinal endoscopy without premedication. Gastroenterol Nurs. 2009;32(5):362. doi:10.1097/SGA.0b013e3181b90111. PMID:19820444.
• Basaranoglu M, Sayilir A, Demirbag AE, Kayacetin S, Tunc B, Arhan M, Kayacetin E, Ulker A. Seasonal variation by the onset of symptoms and health care seeking behaviour in 282 patients with Inflammatory Bowel Disease. Afr J Microbiol Res. 2012;6(28):5782–5788. doi:10.5897/AJMR12.062.